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The initial volume of distribution is a pharmacological term used to quantify the distribution of a drug throughout the body relatively soon after oral or intravenous dosing of a drug and prior to the drug reaching a steady state equilibrium. Following distribution of the drug, measurement of blood levels indicate the apparent volume of distribution. Calculation of the initial volume of distribution is the same calculation as that for the apparent volume of distribution, given by the equation: ::::::: Where: VP = plasma volume VT = apparent tissue volume fu = fraction unbound in plasma fuT = fraction unbound in tissue th:ปริมาตรกระจายตัว 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「initial volume of distribution」の詳細全文を読む スポンサード リンク
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